Hi all,
just after any input / experience regarding leflunomide please. Has anyone taken this and had problems with diarrhoea? I know it is listed as a common side effect but just wondering whether it is a reason to stop taking it or whether it can settle with time.
As some of you know, I had to stop Enbrel about 6 months ago due to suspected infection in my knee replacement and secondary osteomyelitis. During that time, I have only been allowed Depo injections every 6 weeks and no other treatment so the RA has been rampant. I began taking leflunomide 3 weeks ago as this is my only option drug wise at the moment so I'm really desperate to be able to tolerate it.
I have had several bouts of diarrhoea which seem to be getting a lot worse over the last few days. Every time I eat I need the loo, in a hurry! could really do without this on top of everything else, and I cant really afford to lose any more weight.
Any thoughts?
Thanks, Diane x

Hi Diane,Sorry you are having such problems, but I think Naomi is right, get in touch with your rheumy nurse if you can, otherwise ring your G.P who should be able to get in touch with the hospital for you, but hopefully she might be able to suggest something that does not mean you have to come off leflunomide. I was on it for a while but did tolerate it quite well. you could well do without this problem. Hope you get it sorted soon. Zena x.

Thanks girls.
I didnt take the leflu over the weekend. Spoke to my rheumy nurse this morning who advised I stay off it until things return to normal and then re commence it. If the same happens, I won't be able to continue with it.
I feel better in that department today so if the improvement continues tomorrow, I'l try again.
Thanks for listening
Diane x